Evidence over hype

The Skip List

32 supplements and tactics the evidence says most people can stop paying for. Ranked worst value first, from our hand-reviewed worth-it verdicts. Every "Why" links to the full evidence review.

1
Garcinia cambogia / HCA — Worth Your Money?
Weight Loss and Appetite
18/100 · Poor ROI · Trust D
Why
2
Turkesterone
Muscle Building Claims
20/100 · Poor ROI · Trust D
Why
3
Seed Oils — Evidence vs Controversy
General Nutrition / Inflammation
25/100 · Poor ROI · Trust B
Why
4
Spot Reduction Truly Impossible
Fat Loss in a Specific Area (Belly, Arms, Thighs, Hips)
25/100 · Poor ROI · Trust B
Why
5
1200 Calorie Diets — Why They Backfire
Fat Loss for the Broad Adult Population
28/100 · Poor ROI · Trust B
Why
6
Text Neck
Neck Pain Management and Posture Concerns
28/100 · Poor ROI · Trust A
Why
7
Core Stability
Low Back Pain Management — Core Training Decision
30/100 · Poor ROI · Trust A
Why
8
cla body composition
Fat Loss and Body Composition
30/100 · Poor ROI · Trust D
9
Boron — Testosterone, Bone Health, Real Evidence
Bone, Hormones, and Joint Health
32/100 · Poor ROI · Trust D
Why
10
CBD (Cannabidiol)
Anxiety, Pain, and Sleep
32/100 · Poor ROI · Trust D
Why
11
Carnitine — Fat Transport, Who Benefits
Fat Loss and Exercise Performance
42/100 · Low ROI · Trust C
Why
12
Spermidine
Longevity and Cellular Renewal
42/100 · Low ROI · Trust D
Why
13
PQQ
Mitochondrial and Cognitive Support
43/100 · Low ROI · Trust D
Why
14
NMN
Longevity and Healthy Aging
44/100 · Low ROI · Trust D
Why
15
Green Tea Extract / EGCG
Fat Loss and Metabolic Health
44/100 · Low ROI · Trust C
Why
16
HMB — Muscle Retention in Deficit
Muscle Preservation and Recovery
44/100 · Low ROI · Trust D
Why
17
Lion's Mane — Does It Actually Work?
Cognition, Memory, and Nerve Health
44/100 · Low ROI · Trust D
Why
18
Capsaicin / Capsaicinoids
Fat Loss, Metabolism, and Appetite
44/100 · Low ROI · Trust C
Why
19
Resveratrol
Longevity and Cardiovascular Health
45/100 · Low ROI · Trust D
Why
20
Chromium — Blood Sugar, Insulin Sensitivity, Weight Loss
Blood Sugar and Appetite
45/100 · Low ROI · Trust C
Why
21
Post-Workout Nutrition — What Matters, What Doesn't
Hypertrophy and Recovery — Post-Workout Timing Decision
48/100 · Low ROI · Trust A
Why
22
MCT Oil
Fat Loss, Energy, and Ketogenic Support
48/100 · Low ROI · Trust C
Why
23
B-Complex Vitamins — Evidence Review
Energy, Stress, and General Health
50/100 · Low ROI · Trust B
Why
24
Calcium — Bone Density, Heart Risk Debate
Bone Health and Osteoporosis
50/100 · Low ROI · Trust C
Why
25
Vitamin C
Immune Health, Cold Duration, and General Health
52/100 · Low ROI · Trust B
Why
26
Adaptogens Overview
Stress and General Resilience
52/100 · Low ROI · Trust C
Why
27
Spirulina — Evidence Review
General Nutrition and Antioxidant Support
52/100 · Low ROI · Trust C
Why
28
Quercetin
Immune, Allergy, and Anti-inflammatory Support
53/100 · Low ROI · Trust C
Why
29
Selenium — The Verdict Research
Thyroid, Antioxidant, and Immune Support
55/100 · Situational ROI · Trust C
Why
30
Alcohol And Sleep One Drink
Sleep Quality and Recovery
56/100 · Situational ROI · Trust A
Why
31
NAC (N-Acetylcysteine)
Antioxidant, Liver, and Respiratory Support
58/100 · Situational ROI · Trust C
Why
32
Iodine — The Verdict Research
Thyroid Function and Metabolism
60/100 · Situational ROI · Trust B
Why
The part that's about you

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General verdicts are the floor. Whether something is a waste for YOU depends on your goal, budget, and the rest of your stack.

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